Research Articles
Beyond the Coral Reef: Biofluorescence in Temperate Fish Species and Its Emerging Role in Ecology and Biomedical Research
This article synthesizes the rapidly evolving field of biofluorescence in temperate fish species, a phenomenon once thought to be primarily tropical.
Biofluorescence vs Bioluminescence: Mechanisms, Applications, and Strategic Implementation in Biomedical Research
This article provides a comprehensive analysis of the fundamental mechanisms distinguishing biofluorescence and bioluminescence, two pivotal photonic phenomena in life sciences.
Beyond Visual Inspection: Validating a Novel Tongue Biofilm Fluorescence Index for Objective Clinical and Research Applications
The accurate assessment of tongue biofilm is critical for understanding its role in oral and systemic health, yet conventional methods relying on visual inspection are plagued by low inter-examiner reliability.
Indocyanine Green Fluorescence-Guided Surgery: From Fundamental Principles to Clinical Applications and Future Directions
This comprehensive review explores the rapidly evolving field of fluorescence-guided surgery (FGS) using indocyanine green (ICG), a near-infrared fluorophore.
NIR-II Fluorescence Imaging: Revolutionizing Deep-Tissue Visualization for Biomedical Research and Clinical Translation
This article comprehensively explores second near-infrared (NIR-II, 1000–1700 nm) fluorescence imaging, an advanced optical modality offering superior tissue penetration and high-fidelity visualization for preclinical research and emerging clinical applications.
Beyond Jellyfish: The Evolutionary Diversity and Biomedical Applications of GFP Analogs
This article provides a comprehensive exploration of the Green Fluorescent Protein (GFP) family, tracing its phylogenetic journey from its discovery in Aequorea victoria to the vast diversity of analogs found...
Targeted vs. Non-Targeted Fluorescent Agents: A Comparative Analysis of Performance, Applications, and Future Directions in Biomedical Research
This article provides a comprehensive comparative analysis of targeted and non-targeted fluorescent agents, addressing key considerations for researchers, scientists, and drug development professionals.
Validating Fluorescence Lifetime Imaging: A Quantitative Framework for Biomedical Research and Drug Development
Fluorescence Lifetime Imaging Microscopy (FLIM) provides unparalleled quantitative insights into cellular metabolism, protein interactions, and drug efficacy by measuring the nanosecond-scale persistence of fluorophores in an excited state.
Evaluating Fluorescent Probes for Disease Biomarkers: A Comprehensive Guide for Biomedical Research and Drug Development
This article provides a systematic framework for researchers and drug development professionals to evaluate fluorescent probes for specific disease biomarkers.
From Coral Reefs to Clinics: A Comparative Analysis of Biofluorescent Visual Pigments and Their Biomedical Potential
This article provides a comprehensive comparative analysis of visual pigments across biofluorescent species, with a specific focus on implications for drug development and clinical diagnostics.